Archive for the ‘IUI – Intra Uterine Insemination’ Category

How successful would IUI be, if I have PCOS (my eggs don’t mature) and my husband has poor sperm quality. The quantity of his sperm is around 7 million plus minus. There is also a possibility of a chromosome problem with hubby’s sperm … perhaps more of XX chromosomes?? I know that will be dealt with when the sperm is washed. The FS said that we would have anything from a 40% – 60% chance of success and I am presuming that would be 3 cycles. He said that if after 3 cycles we have no success we will move onto IVF. Honestly though do you think our chances would be good taking all of our problems into consideration?

Monday, May 4th, 2009

If the male partner has a chromosomal abnormality that has been documented, the sperm should not be used for IUI at all. Furthermore, the success rate of  IUI’s in people without any problems at all is between 18-20% per attempt. If you have compromised gametes, this chance of success will clearly be less.

- Answers kindly provided by Dr. Stephan Volschenk -

I had a natural IUI cycle cancelled because my lining was only 7mm. I’m going to try again next month using injectables (Menopur).

Monday, May 4th, 2009

Menopur is likely to increase the estrogen level. The growth of the lining is dependant on the amount of estrogen, hence the use of the Menopur. Presumably you have had some sort of cavity assessment to exclude any pathology inside the uterine cavity that might lead to a thin lining?

- Answers kindly provided by Dr. Stephan Volschenk -

I have been for IUI x 2 and they say all the levels are well in the blood test for ovulation and then they say it looks good but in the end still nothing. We are using sperm donors. Am I in too big a rush to see it happen or should I consider another route?

Thursday, March 26th, 2009

There are a few important issues:

-          How old are you?

-          What is your hormone status like?

-          What is the condition of your pelvis and uterine cavity?

-          Are your fallopian tubes open?

 If all of the above are in order and you are 26 years of age, the chance of conceiving per attempt with good quality sperm is around 18% – 20%. This is cumulative over a 3-4 month time period. The older you are the less the chance per attempt.

- Week 32 answers kindly provided by Dr. Stephan Volschenk -

When going for IUI what is the recommended time that one should remain lying down for afterwards? Some FS’s seem to think 2 or 3 minutes is sufficient while others allow their patient 10 – 15 minutes.

Friday, January 30th, 2009

The latest publications suggest a period of 15 minutes.

- Bi-Week 30 answers kindly provided by Dr. Stephan Volschenk -

We have had 3 Full SA, always between 8- 10 million and morphology of 3-4. But the pre-spun Semen count is between 20 and 30 million everytime we do IUI. Will this be accurate? Can we say that the count has increased?

Monday, July 21st, 2008

The count has not increased. What you are looking at when it has been prepared for AI is a concentrated count.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

What is the chance of successful IUI if total count on Full SA was 10 Mil and 4% morphology and 55 % motility? Is it worth pursuing or should we move onto IVF immediately?

Monday, July 21st, 2008

Total count on full SA being 10 mil/ml is on the low side. One would therefore be inclined to move onto IVF/ICSI sooner rather than later.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

I have had 4 rounds of IUI. This last round I had slight cramps directly after IUI wich lasted for a couple of hours. I have never had these cramps with any previous IUI’s. What could the reason for cramping be? I found out today that there are 2 types of catheters used for IUI. A ‘thin’ one and a ‘soft’ one. What is the reason for two different types?

Monday, July 21st, 2008

Cramping post AI is not necessarily a bad sign. It is due to the presence of the sperm and media inside the uterus. A uterus always aims to be empty and therefore contracts in order to rid itself of anything on the inside but instead sucks the sperm into the fallopian tubes. It therefore varies from cycle to cycle and also might be due to a change in the media the sperm is prepared in.

With regards to the catheters: There are many types of insemination catheters. Some harder or softer than others. Which one is used usually depends on the clinician, in other words which he/she is comfortable in using.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

When doing IUI, what is the correct protocol to follow? Trigger on Follicle size 18mm and insemination 24 hrs later? How important are these timeframes?

Thursday, May 8th, 2008

As soon as the correct follicle size has been reached, ovulation should be triggered and the insemination should follow within the next 35 to 44 hours. Some clinics will do 2 consecutive IUI’s, following the trigger and some just one.

- Week 13 answers kindly provided by Dr. Stephan Volschenk -

I have a question. I would like to find out if they could do a IUI with Sperm Aspiration? I have read that you can and I have also read that you can’t cause there are not enough sperm that can swim seeing that they only stat getting their “swimming abilities” when passed through the tubes? If the reason for aspiration is the fact that my husband has had a vasectomy and not because of fertility issues, would IUI with aspirated sperm not be a possibility?

Thursday, May 8th, 2008

When attempting an IUI, the following parameters should be kept in mind:
1)    Morphology more than 4%
2)    Inseminated motile count of more than 1 million/ml
3)    50% motility.

Unfortunately, with a sperm aspiration one would never be able to get to these parameters and therefore IUI with aspirated sperm will not be possible. Apart from that there is also the fact that sperm need to spend some time in the epididymus of the testicle in order to mature and have the ability to fertilise an oocyte. The only option would therefore be sperm extraction and ICSI.

- Week 13 answers kindly provided by Dr. Stephan Volschenk -


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